Men’s health & testosterone in Newtown, PA
Physician-supervised, integrated with the rest of your care, and built on a complete workup — not a single morning lab and a symptom checklist.
Signature Medicine prescribes testosterone replacement therapy when indicated by a complete workup, with the cardiovascular, sleep, prostate, and longevity picture in the same chart. Dr. Sitapara is the prescribing physician across the whole plan, not a separate provider for each piece.
What’s included
- Extended initial workup with Dr. Sitapara
- Comprehensive labs: total + free testosterone, LH, FSH, SHBG, prolactin, estradiol, lipid panel, A1C, CBC, comprehensive metabolic panel, PSA, vitamin D
- Cardiovascular risk assessment integrated with overall preventive care
- Sleep-apnea screening — a common underlying driver of low testosterone that med-spa models miss
- Prostate health discussion and monitoring cadence
- TRT prescribing when indicated (injectable, transdermal, or pellet pathways)
- Adjacent medications when clinically appropriate (anastrozole, hCG for fertility preservation)
- InBody scan to track body composition over the course of therapy
- Ongoing monitoring at evidence-based intervals — not whenever the clinic reminds you
Why integrated matters
TRT clinics run testosterone protocols in isolation. That model produces predictable problems: cardiovascular risk that no one is tracking, sleep apnea that turns out to be doing more work than the prescription, hematocrit elevations that need management, and fertility concerns that come up too late. At Signature Medicine, the TRT decision sits inside a longitudinal plan with Dr. Sitapara — the same doctor who manages your annual labs and your cardiovascular risk runs the testosterone conversation.
Transitioning from another TRT clinic
We work with many members who started TRT elsewhere and want to transition to a longitudinal primary care relationship. Dr. Sitapara reviews the original workup (often re-done because it was incomplete), the current regimen, and re-anchors the plan to your overall health picture.
Frequently Asked Questions
Does Signature Medicine prescribe testosterone replacement therapy (TRT)?
Yes, when indicated by a complete workup. Dr. Sitapara prescribes TRT for men with confirmed low testosterone and an honest discussion of symptoms, goals, and risk-benefit framing. We do not prescribe testosterone based on a single morning lab and a symptom checklist — that is the med-spa model and it produces problems downstream.
What does a men's health workup at Signature Medicine include?
An extended visit with Dr. Sitapara, comprehensive labs (total + free testosterone, LH, FSH, SHBG, prolactin, estradiol, lipid panel, A1C, complete metabolic panel, PSA, vitamin D, complete blood count), cardiovascular risk assessment, sleep-apnea screening (often a driver of low testosterone that goes missed), prostate health discussion, and shared decision-making on therapy options.
How is this different from a TRT clinic or med-spa?
TRT clinics and med-spas typically operate one-size-fits-all protocols without integrated primary care. They run testosterone, look at testosterone, and adjust testosterone. Signature Medicine puts the testosterone conversation inside the larger one: your cardiovascular risk, sleep, body composition, fertility goals, prostate health, and longevity plan all live in the same chart and inform the prescription decisions.
I'm on TRT through a clinic now — can I transition my care?
Yes. Many of our members come to us already on TRT after their clinic prescription gets harder to maintain, follow-up drops off, or coverage changes. Dr. Sitapara reviews the regimen, the underlying workup (often re-done because it was incomplete), and re-anchors the plan to your overall health picture.
Does the membership cover medication cost?
No. The membership fee covers physician care, workup, and ongoing monitoring. Testosterone and adjacent medications (anastrozole, hCG, etc. when indicated) are billed to your insurance or paid out of pocket. We help with prior authorization and discuss out-of-pocket options when coverage is denied.
Last reviewed by Dr. Ashish Sitapara, MD, FACP on